1-832-868-1888
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Catalog Number: |
28866 |
| other_names: | ULBP2; ALCAN-alpha; N2DL2; NKG2DL2; RAET1H; NKG2D ligand 2 |
Amount: |
100μg |
| calculated_mw: | Refer to figures |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:Q9BZM5 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human ULBP2 (NP_079493.1). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IF |
Background: |
This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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