RTN3 Polyclonal Antibody

Catalog Number:

28835

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O95197
NCBI Gene ID:10313

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

A synthetic synthetic peptide of human RTN3 (NP_006045.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF