HERC5 Polyclonal Antibody

Catalog Number:

28743

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UII4
NCBI Gene ID:51191

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human HERC5 (NP_057407.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF