ERLIN1 Polyclonal Antibody

Catalog Number:

28725

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O75477
NCBI Gene ID:10613

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human ERLIN1 (NP_006450.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF