EIF4G3 Polyclonal Antibody

Catalog Number:

28650

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O43432
NCBI Gene ID:8672

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human EIF4G3 (NP_003751.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF