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Catalog Number: |
27564 |
other_names: | SPTLC2; HSN1C; LCB2; LCB2A; NSAN1C; SPT2; hLCB2a; serine palmitoyltransferase 2 |
Amount: |
100μg |
calculated_mw: | 58kDa |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:O15270 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human SPTLC2 (NP_004854.1). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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