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PPFIA1 Polyclonal Antibody

Catalog Number:

27413
other_names: PPFIA1; LIP.1; LIP1; LIPRIN; liprin-alpha-1

Amount:

100μg
calculated_mw: 136kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q13136
NCBI Gene ID:8500

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human PPFIA1 (NP_003617.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.

References:

appl_detail:

WB 1:500 - 1:2000

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