NBN Polyclonal Antibody

Catalog Number:

27241

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O60934
NCBI Gene ID:4683

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human NBN (NP_002476.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

References:

appl_detail:

WB 1:500 - 1:1000

Datasheet PDF