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Slc30A8 Antibody

Catalog Number:

26049
other_names: Zinc transporter 8; ZnT-8; ZNT8

Amount:

100μg
calculated_mw: 41kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8IWU4
NCBI Gene ID: 169026
NCBI Protein#: NP_776250.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

KLH-conjugated synthetic peptide

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total Slc30A8 protein.

Applications:

WB

Background:

 Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells.
 
Chimienti F., Devergnas S., Favier A., Seve M.Diabetes 53:2330-2337(2004)                                             
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.BMC Genomics 8:399-399(2007)          
 

References:

appl_detail:

 Western blotting: 1:500~1:1000

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