1-832-868-1888
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Catalog Number: |
25161 |
other_names: | Homeobox protein VENTX, HPX42B, MGC119910, VENTX2, NA88A |
Amount: |
100μg |
calculated_mw: | |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:O95231 |
Form of Antibody: |
Supplied in PBS containing 0.02% sodium azide. |
Storage/Stability: |
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Immunogen: |
Raised against a 16 amino acid peptide near the center of human VENTX. |
Purification: |
Affinity chromatography purified via peptide column |
Specificity/Sensitivity: |
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Applications: |
ELISA WB IHC |
Background: |
Lymphoid-enhancing factor/T-cell factors (LEF1/TCF) are a high-mobility group of transcriptional factors that play essential roles in cell fate determination during early embryogenesis and ontogenesis. VENTX is a member of the Vent family of homeodomain proteins. It is a novel LEF/TCF-associated transcriptional modulator. VENTX is predominately expressed in hematopoietic cells. VENTX may function as a transcriptional repressor and be involved in mesodermal patterning and hemapoietic stem cell maintenance, and has been suggested to have a potential role in the hematopoietic malignancies. |
References: |
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appl_detail: |
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