RUSC2 Antibody

Catalog Number:

24976

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8N2Y8
Gene ID:9853

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 15 amino acid peptide from near the carboxy terminus of human RUSC2.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least three isoforms are known to exist; this antibody will only detect the longest isoform. This antibody is predicted to not cross-react with RUSC1.

Applications:

ELISA IHC

Background:

RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.

References:

appl_detail:

Datasheet PDF