ZIP10 Antibody

Catalog Number:

24824

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9ULF5
Gene ID:57181

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 17 amino acid peptide near the center of the human ZIP10.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

This antibody will not cross-react with the zinc transporter ZIP11.

Applications:

ELISA WB IHC

Background:

ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist.

References:

appl_detail:

Datasheet PDF