1-832-868-1888
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Catalog Number: |
24716 |
other_names: | Cytoplasmic polyadenylation element-binding protein 1, CPE-B1, CEBP |
Amount: |
100μg |
calculated_mw: | |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Q9BZB8 |
Form of Antibody: |
Supplied in PBS containing 0.02% sodium azide. |
Storage/Stability: |
|
Immunogen: |
Raised against a 14 amino acid peptide from near the amino terminus of human CPEB1. |
Purification: |
Affinity chromatography purified via peptide column |
Specificity/Sensitivity: |
|
Applications: |
ELISA WB |
Background: |
CPEB1 is an RNA binding protein that contains an RNA-recognition motif and a zinc finger-containing region found in a wide range of vertebrates and invertebrates. CPEB1 forms the nucleus of a complex of factors that regulate poly(A) elongation and promotes polyadenylation-induced translation. CPEB1 mediates many diverse biological processes such as germ cell development, cell division and senescence, and synaptic plasticity. Recently, it was discovered that CPEB1 is involved in beta-catenin mRNA translation and cell migration in astrocytes as well as regulating hypoxia-inducible factor (HIF)-1 expression, demonstrating the wide range of processes in which CPEB1 plays a role. At least four isoforms of CPEB1 are known to exist. |
References: |
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appl_detail: |
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