Avian Influenza Nonstructural Protein 2 Antibody

Catalog Number:

24453

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q2L6Z2
Gene ID:

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a synthetic peptide corresponding to 14 amino acids near the middle of the Avian Influenza Nonstructural Protein 2 protein. Efforts were made to use relatively conserved regions of the viral sequence as the antigen.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Applications:

ELISA

Background:

Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however, it is in birds that all subtypes, including the so-called "avian flu" or H5N1, can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. One of the less studied proteins encoded by the influenza virus is the nonstructural protein (NS) 2. NS2 binds to the influenza matrix protein M1 that is bound to the ribonucleoprotein (RNP) complex and mediates the contact between the M1/RNP complex and the cellular exportin CRM, but does not interact with nucleosomes.

References:

appl_detail:

Datasheet PDF