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Unc93a Antibody

Catalog Number:

24664
other_names: Unc93a, homolog of C. elegans Unc93

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q86WB7
Gene ID:54346

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 18 amino acid peptide from near the carboxy terminus of human Unc93a.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Two isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93b.

Applications:

ELISA WB

Background:

Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a. Unlike Unc93b, another homolog of the C. elegans Unc93 gene that is crucial for Toll-like receptor (TLR) signaling, the function of Unc93a is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary.

References:

appl_detail:

Datasheet PDF

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