1-832-868-1888
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Catalog Number: |
24375 |
other_names: | B cell receptor-associated protein 29, BCR associated protein 29 |
Amount: |
100μg |
calculated_mw: | |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:Q9UHQ4 |
Form of Antibody: |
Supplied in PBS containing 0.02% sodium azide. |
Storage/Stability: |
|
Immunogen: |
Raised against a 17 amino acid peptide from near the center of human Bap29 Bap29 antibody is specific for isoform a of Bap29. |
Purification: |
Affinity chromatography purified via peptide column |
Specificity/Sensitivity: |
|
Applications: |
ELISA WB IHC |
Background: |
Bap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors. Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins. Bap29 possesses multiple isoforms. |
References: |
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appl_detail: |
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