TLR1 Antibody

Catalog Number:

24362

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q15399
Gene ID:7096

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a peptide corresponding to 17 amino acids near the center of human TLR1.

Purification:

Ion exchange chromatography purified

Specificity/Sensitivity:

Applications:

ELISA WB ICC

Background:

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins.

References:

appl_detail:

Datasheet PDF