Caspase-13 Antibody

Catalog Number:

24097

Amount:

100μg

Price:

$319

Swiss-Prot No:

O75601

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a peptide corresponding to amino acids 91 to 105 of human caspase-13.

Purification:

Ion exchange chromatography purified

Specificity/Sensitivity:

Applications:

ELISA WB IHC

Background:

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.

References:

appl_detail:

Predicted MW: 43 kd

Datasheet PDF