Bonzo Antibody

Catalog Number:

24034

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O00574
Gene ID:10663

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a peptide corresponding to amino acids 319 to 338 of human origin. The sequence of. This peptide is identical to those of macaque and African green monkey.

Purification:

DEAE purified

Specificity/Sensitivity:

Applications:

ELISA WB

Background:

Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor. Bonzo/STRL33 is used by SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.

References:

appl_detail:

Datasheet PDF