ML-IAP antibody

Catalog Number:

22924

Amount:

100μg

Price:

$319

Swiss-Prot No:

NCBI Gene ID: 79444
NCBI mRNA#: BC014475
NCBI Protein#: AAH14475

Form of Antibody:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

A synthesized peptide derived from human ML-IAP

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq]

References:

appl_detail:

Predicted MW: 33kd
Western blotting: 1:100-1:3000

Datasheet PDF