HMGA2 antibody

Catalog Number:

22874

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P52926
Gene ID:8091

Form of Antibody:

Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 93 of Human HMGA2

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

WB IHC

Background:

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

References:

appl_detail:

Predicted MW: 12kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:50-1:500
 

Datasheet PDF