Homer-3 antibody

Catalog Number:

22744

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NSC5
Gene ID:9454

Form of Antibody:

Supplied in 0.1M Tris-buffered saline with 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 55 and 275 of Homer-3

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Predicted MW: 40kd
Western blotting: 1:500-1:3000

Datasheet PDF