Complement factor H antibody

Catalog Number:

22665

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P08603
Gene ID:3075

Form of Antibody:

Supplied in 1XPBS, 1%BSA, 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

527 - 588 of Human Complement factor H

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

WB

Background:

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

References:

appl_detail:

Predicted MW: 139kd
Western blotting: 1:500-1:3000

Datasheet PDF