1-832-868-1888
order@swbio.com
Catalog Number: |
22661 |
other_names: | |
Amount: |
100μg |
calculated_mw: | |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:P27930 |
Form of Antibody: |
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. |
Storage/Stability: |
|
Immunogen: |
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 172 and 391 of IL1R2 |
Purification: |
Purified by antigen-affinity chromatography. |
Specificity/Sensitivity: |
|
Applications: |
WB IHC IF |
Background: |
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq] |
References: |
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appl_detail: |
Predicted MW: 45kd |
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