Dyrk3 antibody

Catalog Number:

22581

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O43781
Gene ID:8444

Form of Antibody:

Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 243 and 542 of Dyrk3

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

WB

Background:

This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

References:

appl_detail:

Predicted MW: 64kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:500

Datasheet PDF