TRADD antibody

Catalog Number:

22562

Amount:

100μg

Price:

$319

Swiss-Prot No:

NCBI Gene ID: 8717
NCBI mRNA#: NM_003789
NCBI Protein#: NP_003780

Form of Antibody:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

A synthesized peptide derived from human TRADD

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

WB IHC IF

Background:

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq]

References:

appl_detail:

Predicted MW: 34kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:50-1:200

Datasheet PDF