1-832-868-1888
order@swbio.com
Catalog Number: |
22433 |
other_names: | |
Amount: |
100μg |
calculated_mw: | |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:O15353 |
Form of Antibody: |
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. |
Storage/Stability: |
|
Immunogen: |
Synthetic peptide contain a sequence corresponding to a region within amino acids 585 and 648 of Human FOXN1 |
Purification: |
Purified by antigen-affinity chromatography. |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq] |
References: |
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appl_detail: |
Predicted MW: 69kd |
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