1-832-868-1888
order@swbio.com
Catalog Number: |
22150 |
other_names: | |
Amount: |
100μg |
calculated_mw: | |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:Q9UGJ0 |
Form of Antibody: |
Supplied in 0.1M Tris-buffered saline with 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. |
Storage/Stability: |
|
Immunogen: |
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 342 and 525 of AMPK gamma-2 |
Purification: |
Purified by antigen-affinity chromatography. |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
References: |
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appl_detail: |
Predicted MW: 58kd |
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