7-Sep antibody

Catalog Number:

22091

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q16181
Gene ID:989

Form of Antibody:

Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 192 and 411 of Human 7-Sep

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

WB IHC

Background:

This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. Although the exact function of this gene has not yet been determined, its high similarity to yeast CDC10 and the high conservative nature of eukaryotic cell cycle machinery suggest a similar role to that of its yeast counterpart. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]

References:

appl_detail:

Predicted MW: 51kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:250

Datasheet PDF