a-Internexin Antibody

Catalog Number:

21638

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q16352
NCBI Protein: NP_116116.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.491~495 (E-T-T-I-S

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total a-Internexin protein.

Applications:

WB

Background:

Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.

Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. Science 316:1160-1166(2007)

References:

appl_detail:

Predicted MW: 66kd
Western blotting: 1:500~1:1000

Datasheet PDF