MAP2 Antibody

Catalog Number:

21636

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P11137
NCBI Protein: NP_002365.3

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.1819~1823 (T-A-A-L-A) derived from Human MAP2.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total MAP2 protein.

Applications:

WB IF

Background:

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

DeGiorgis J.A., Jaffe H., Moreira J.E., Carlotti C.G. Jr. Proteome Res. 4:306-315(2005)
Olsen J.V., Blagoev B., Gnad F., Macek B. Mann M.Cell 127:635-648(2006)
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. Science 316:1160-1166(2007)

References:

appl_detail:

Predicted MW: 55-75(2c/2d), 280(2a/2b)kd
Western blotting: 1:500~1:1000
Immunofluorescence: 1:100~1:200

Datasheet PDF