VEGFR1 Antibody

Catalog Number:

21631

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P17948
NCBI Protein: NP_002010.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.31~35 (D-P-E-L-S) derived from Human VEGFR1.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total VEGFR1 protein.

Applications:

WB

Background:

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

Rikova K., Guo A., Zeng Q., Possemato A. Cell 131:1190-1203(2007)

References:

appl_detail:

Predicted MW: 180kd
Western blotting: 1:500~1:1000

Datasheet PDF