Neuroserpin Antibody

Catalog Number:

21618

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q99574
NCBI Protein: NP_001116224.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.402~406(T-S-G-H-D) derived from Human Neuroserpin.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total Neuroserpin protein.

Applications:

WB

Background:

Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.

Davis R.L., Shrimpton A.E., Holohan P.D. Nature 401:376-379(1999)

References:

appl_detail:

Predicted MW: 55kd
Western blotting: 1:500~1:1000

Datasheet PDF