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Catalog Number: |
21539 |
other_names: | KIT; CD117; SCFR; PBT; |
Amount: |
100μg |
calculated_mw: | |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot: P10721 |
Form of Antibody: |
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage/Stability: |
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Immunogen: |
Peptide sequence around aa.934~938 (H-I-Y-S-N) derived from Human c-Kit. |
Purification: |
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Specificity/Sensitivity: |
The antibody detects endogenous level of total c-Kit protein. |
Applications: |
WB IHC |
Background: |
This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)
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References: |
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appl_detail: |
Predicted MW: 145kd |
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