CtIP antibody

Catalog Number:

22632

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q99708
Gene ID:5932

Form of Antibody:

Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 452 and 747 of CtIP

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq]

References:

appl_detail:

Predicted MW: 102kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:500

Datasheet PDF