beta-glucosidase antibody

Catalog Number:

22358

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P04062
Gene ID:2629

Form of Antibody:

Supplied in 0.1M Tris-buffered saline with 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 65 and 354 of beta-glucosidase

Purification:

Purified by antigen-affinity chromatography.

Specificity/Sensitivity:

Applications:

WB IHC

Background:

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]

References:

appl_detail:

Predicted MW: 60kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:500

Datasheet PDF