GATA-4 Antibody

Catalog Number:

21496

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P43694
NCBI Protein: NP_002043.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.434~438(D-S-H-G-D) derived from Human GATA-4.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total GATA-4 protein.

Applications:

WB

Background:

Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5

Garg V., Kathiriya I.S., Barnes R., Schluterman M.K., King I.N., Butler C.A., Rothrock C.R., Eapen R.S., Hirayama-Yamada K., Joo K., Matsuoka R., Nature 424:443-447(2003)
Hirayama-Yamada K., Kamisago M., Akimoto K., Aotsuka H., Nakamura Y., Tomita H., Furutani M.,Matsuoka R.Am. J. Med. Genet. A 135:47-52(2005)

References:

appl_detail:

Predicted MW: 50kd
Western blotting: 1:500~1:1000

Datasheet PDF