CD11c Antibody

Catalog Number:

21491

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P20702
NCBI Protein: NP_000878.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.1155~1159(Q-T-P-S-P)derived from Human CD11c.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total CD11c protein.

Applications:

WB

Background:

Integrin a-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.J. Proteome Res. 8:651-661(2009)

References:

appl_detail:

Predicted MW: 145kd
Western blotting: 1:500~1:1000

Datasheet PDF