CD34 Antibody

Catalog Number:

21469

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P28906
NCBI Protein: NP_001020280.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.377~381(Q-H-V-V-A) derived from Human CD34.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total CD34 protein.

Applications:

WB

Background:

Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.

Fackler M.J.et.al(1990)Chem. 265:11056-11061

References:

appl_detail:

Predicted MW: 110kd
Western blotting: 1:500~1:1000

Datasheet PDF