Lymphatic vessel endothelial hyaluronic acid receptor 1 Antibody

Catalog Number:

21407

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9Y5Y7
NCBI Protein: NP_006682.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.271~275 (K-N-Q-Q-K) derived from Human Lymphatic vessel endothelial hyaluronic acid receptor 1.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total Lymphatic vessel endothelial hyaluronic acid receptor 1 protein.

Applications:

WB

Background:

Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Heindl LM, et al. (2010) Ophthalmology.117(2):334-42.
He P et al.(2006) Lin Chuang Er Bi Yan Hou Ke Za Zhi.20(18):828-30, 833.
Lim HY,et al. (2009) Am J Pathol.175(3):1328-37.

References:

appl_detail:

Predicted MW: 40kd
Western blotting: 1:500~1:1000

Datasheet PDF