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Catalog Number: |
12146 |
| other_names: | KIAA0827; NF-AT5; nuclear factor of activated T cells 5; T cell transcription factor NFAT5; TonE-binding protein; TonEBP; tonicity-responsive enhancer-binding protein |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:O94916; |
Form of Antibody: |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage/Stability: |
|
Immunogen: |
Peptide sequence around phosphorylation site of serine 155 (D-N-S(p)-R-M) derived from Human NFAT5/TonEBP. |
Purification: |
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi |
Specificity/Sensitivity: |
The antibody detects endogenous levels of NFAT5/TonEBP only when phosphorylated at serine 155. |
Applications: |
WB |
Background: |
Transcription factor involved in the transcriptional regulation of osmoprotective and inflammatory genes. Regulates hypertonicity-induced cellular accumulation of osmolytes. |
References: |
|
appl_detail: |
Western blotting: 1:500~1:3000 |
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