MNK1 (Phospho-Thr255) Antibody

Catalog Number:

12142

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9BUB5;
NCBI Gene#:8569

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of threonine 255 (L-T-T(p)-P-C) derived from Human MNK1.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of MNK1 only when phosphorylated at threonine 255.

Applications:

WB

Background:

May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF