FANCG (Phospho-Ser383) Antibody

Catalog Number:

12138

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O15287;
NCBI Gene#:2189

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of serine 383 (R-F-S(p)-P-P) derived from Human FANCG.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of FANCG only when phosphorylated at serine 383.

Applications:

WB

Background:

DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF