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ALOX5 (Phospho-Ser523) Antibody

Catalog Number:

12128
other_names: 5-lipoxygenase; 5-LO; 5-LOX; 5LPG; ALOX5; Arachidonate 5-lipoxygenase; arachidonic acid 5-lipoxygenase; leukotriene A4 synthase; LOG5; LOX5; MGC163204

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P09917;
NCBI Gene#:240

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of serine 523 (R-K-S(p)-K-G) derived from Human ALOX5.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of ALOX5 only when phosphorylated at serine523.

Applications:

WB

Background:

Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.

References:

appl_detail:

Western blotting: 1:500~1:3000

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