TNFRSF5 (Phospho-Thr254) Antibody

Catalog Number:

12109

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P25942;
NCBI Gene#:958

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of threonine 254 (Q-E-T(p)-L-H) derived from Human TNFRSF5.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of TNFRSF5 only when phosphorylated at threonine 254.

Applications:

WB

Background:

Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF