HBP1 (Phospho-Ser402) Antibody

Catalog Number:

12107

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O60381;
NCBI Gene#:26959

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of serine 402 (C-G-S(p)-P-G) derived from Human HBP1.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of HBP1 only when phosphorylated at serine 402.

Applications:

WB

Background:

Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF