Histone H3(Phospho-Ser10) Rabbit Polyclonal Antibody

Catalog Number:

12084

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P68431

Form of Antibody:

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of serine 10(R-K-S(p)-T-G) derived from Human Histone H3.

Purification:

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Specificity/Sensitivity:

The Histone H3(Phospho Ser10) Rabbit Polyclonal Antibody detects endogenous Histone H3(Phospho Ser10) protein.

Applications:

WB

Background:

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

References:

appl_detail:

Western blotting: 1:500~1:1000

Datasheet PDF