DRP-2 (Phospho-Thr514) Antibody

Catalog Number:

12055

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q16555;
NCBI Gene#: 1808;
NCBI Protein#: NP_001184222.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of Threonine 514 (K-V-T(p)-P-A) derived from Human DRP-2.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous level of DRP-2 only when phosphorylated at Threonine 514.

Applications:

WB

Background:

Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton By similarity. Plays a role in neuron projection morphogenesis.

References:

appl_detail:

Predicted MW: 65-70kd
Western blotting: 1:500~1:1000

Datasheet PDF