GATA4 (Phospho-Ser262) Antibody

Catalog Number:

12043

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P43694;
NCBI Gene#: 2626;
NCBI Protein#: NP_002043.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of Serine 262 (R-L-S(p)-A-S) derived from Human GATA4.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous level of GATA4 only when phosphorylated at Serine 262.

Applications:

WB

Background:

Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5 By similarity. Promotes cardiac myocyte enlargement.

References:

appl_detail:

Predicted MW: 48kd
Western blotting: 1:500~1:1000

Datasheet PDF