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ATRIP (Phospho-Ser68) Antibody

Catalog Number:

12035
other_names: TREX1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8WXE1;
NCBI Gene#: 84126;
NCBI Protein#: NP_001257951.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of Serine 68 (L-A-S(p)-Q-A) derived from Human ATRIP.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous level of ATRIP only when phosphorylated at Serine 68.

Applications:

WB

Background:

Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.

References:

appl_detail:

Predicted MW: 80kd
Western blotting: 1:500~1:1000

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